- Uplyft: Connecting People with Primary Lymphedema I was born with primary lymphedema (PL)—a rare, congenital, progressive and chronic swelling affecting primarily the limbs, leading to distortion in size, shape and even function, in my left arm and intestines. PL is caused by a failure in the lymphatic system and contributes to an individual’s physical, social, emotional, and psychological distress. Furthermore, without […]